RAPID-ACTING INSULINS

RAPID-ACTING INSULINS

F.Sarvghadi MD

Associate professor of endocrinology.

Research institute for endocrine sciences

Shahid Beheshti University

Of Medical Sciences

AGENDA

Introduction
Pharmacokinetic Properties of Insulin
Molecular Structure & Dosage Forms
Lispro
Glulisine
Aspart
Comparison between Insulin Regular & Rapid-Acting Insulin in DM1(HbA1C Reduction, rate of Hypoglycemia ,Quality of Life)
Comparison between Insulin Regular & Rapid-Acting Insulin in DM2(HbA1C Reduction ,rate of Hypoglycemia , Quality of Life)
Rapid –Acting Insulin in Pregnancy
Rapid –Acting Insulin in Elderly
Conclusion

Introduction

Insulin has been commercially available since the early 1920s and is still the mainstay of therapy for most people with DM worldwide.
Currently, almost all insulin

used worldwide is of recombinant

human origin or an analogue.